Совместимость Клоназепам и Дифенин
Страница описания препарата Клоназепам
Страница описания препарата Дифенин
Cтепень серьёзности/тяжести
Достоверность
Описание взаимодействия
Источники
Печатные издания
Phenytoin toxicity due to interaction with clobazam
Neurology /Volume:41 Part:2/Feb Page:313-4 / 1991
Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin
Epilepsia /Volume:37 Part:3/Mar Page:253-7 / 1996
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine
Acta Neurol Scand /Volume:55 Part:6/Jun Page:506-12 / 1977
Oxazepam pharmacokinetics in patients with epilepsy treated longterm with phenytoin alone or in combination with phenobarbitone
Br J Clin Pharmacol /Volume:16 Part:4/Oct Page:441-4 / 1983
Pharmacokinetic and pharmacodynamic consequences of metabolism-based drug interactions with alprazolam, midazolam, and triazolam
J Clin Pharmacol /Volume:39 Part:11/Nov Page:1109-25 / 1999
Phenytoin-diazepam interaction
Ann Pharmacother /Volume:37 Part:5/May Page:659-63 / 2003
Phenytoin/clonazepam interaction
Ther Drug Monit /Volume:7 Part:4 Page:481-4 / 1985
Cтепень серьёзности/тяжести
Достоверность
Описание взаимодействия
Источники
Dhillon S, Richens A. Valproic acid and diazepam interaction in vivo. Br J Clin Pharmacol (1982) 13, 553-60
Yukawa E, Nonaka T, Yukawa M, Higuchi S, Kuroda T, Goto Y. Pharmacoepidemiologic investigation of a clonazepam-valproic acid interaction by mixed effect modeling using routine clinical pharmacokinetic data in Japanese patients. J Clin Pharm Ther (2003) 28, 497–504
Stockley's Drug Interaction, Twelfth edition, Pharmaceutical Press (2019), p.891, 893-894, 910, 920
Cтепень серьёзности/тяжести
Достоверность
Описание взаимодействия
Источники
Stockley's Drug Interaction, Twelfth edition, Pharmaceutical Press (2019), p.875